These guys are speedrunning a shittttton of games to help fund cancer research. Their drive ends on the 20th and they have already raised $77,470 since starting this today.
[twitchtv]speeddemosarchivesda[/twitchtv]
It's a fun watch. A guy just finished speedrunning amnesia and it was amazing. They are about to speed run l4d. Their schedule for stuff is on the website.