All of Promathia's WS seem to be Dark based, so Lux Wards do great against him. The only difference between phase 1 and 2 seems to be Meteor and extra WSs, which are specifically the shields, and the silence and amnesia ones. The plague and curse moves are possible in phase one.
Omega is pretty simple. For Ultima, using Vex can help outright resist Nuclear Waste. Haven't tried VD yet though, so I'll see how reliable that is.