Green Bay (10-1) @ Dallas (10-1): I'm going with Green Bay on this one. I expect this to be a really good and really close game. Personally I think Green Bay has a better secondary that should be able handle Romo and his offense. I honestly don't think TO will have that big of a game because he'll have Al Harris on him the whole time. People have questioned Green Bay's running game but they have found a pretty good running back in Ryan Grant; he's not great but he can definitely set up the play-action for Favre as well as prevent too many 3rd and Longs. I find GB's defense to be more aggressive and consistent.
Detroit (6-5) @ Minnesota (5-6): Even without Adrian Peterson, Minnesota can play pretty well on offense (with Chester Taylor that is), but the Vikings get AP back this week. Despite having people like Shaun Rogers, I don't think the Lions will be able to stop the powerful one-two punch of Taylor and Peterson. The Detroit offense has been incredibly out of sync lately and the good run defense of Minnesota should be able to stop Kevin Jones.
Seattle (7-4) @ Philadelphia (5-6)
San Diego (6-5) @ Kansas City (4-7) Picking KC for the upset here. With the good CBs that KC has, I don't think Philip Rivers will have a very good game and LT hasn't been playing like he was last season.
New York Jets (2-9) @ Miami (0-11) Despite having an 0-11 record, Miami has lost 5-6 of their games by only 3 points. I think Beck will get his first win as a starter in this game and Miami to go at least 1-15.
Jacksonville (8-3) @ Indianapolis (9-2) Indy still has all those injuries and Jacksonville seems to be getting better and better, especially with the return of David Garrard. I'm picking Indy to win, but I think it will be a pretty close game, and not a blowout like what happened when these two teams faced each other earlier in the season.
San Fransisco (3-8) @ Carolina (4-7)
Houston (5-6) @ Tennessee (6-5) Houston for the upset.
Atlanta (3-8) @ St. Louis (2-9)
Buffalo (5-6) @ Washington (5-6)
Cleveland (7-4) @ Arizona (5-6)
Denver (5-6) @ Oakland (3-8)
New York Giants (7-4) @ Chicago (5-6) I think the Giants will have another season where they perform very well the first half of the season, then fall in to a ditch the second half. Picking Chicago here for the upset; seeing that Chicago's defense is playing a little bit better, seeing that the Bears Adrian Peterson will probably provide Chicago with a running game, and seeing that Grossman isn't flinging the ball in to the air like a moron.
Tampa Bay (7-4) @ New Orleans (5-6)
Cincinnati (4-7) @ Pittsburgh (8-3) I was going to pick the Bengals for the upset, but I think the Steelers will win this. However, I think it will be a close game rather than a blowout.
New England (11-0) @ Baltimore (4-7) New England; hands down. Baltimore having a good run D doesn't mean crap against the Patriots. Baltimore has no offense and an old defense.