AFC
Jacksonville (11-5) @ Pittsburgh (10-6) - I'm going with Jacksonville all the way on this one. The Steelers lost their team's identity with the loss of Willie Parker and I don't think Davenport will be able to take over on the RB position. In the books, Pittsburgh's defense looks really good, but they haven't been playing well at all over the past few games. The powerful one-two punch running game of Taylor and MJD will be way too much for the Steelers to handle. Don't forget that David Garrard is playing smart and consistent football and has been steadily improving his passing game. I don't think Pittsburgh is going to get killed, but I think the Jags will win by at least a TD.
Tennessee (10-6) @ San Diego (11-5) - Well, I really wanted the Browns to go to the playoffs but Peyton and Company couldn't wrap up the game against the Titans in the first half. The Chargers started the season very poorly but they seem to have recollected themselves and have become dominant once again. Both these teams have pretty good defenses and both have offenses that can be incredibly inconsistent at times. If Philip Rivers doesn't throw a bunch of INTs and LT has enough touches, I forsee the Chargers winning this game pretty easily. I don't think the Titans Offense will be productive against the Chargers.
NFC
Washington(9-7) @ Seattle (10-6) - I think this game should be pretty interesting. It's safe to say now that the Seahawks are a passing team this season. Running the ball is probably taboo in Seattle now. That means that Hasselbeck and Co. will have to go up against a determined defense that has been on a roll in the past 4 games. Then you have Clinton Portis, Todd Collins, Santana Moss, and Chris Cooley coming together in a perfect harmony on offense. Despite having a 9-7 record, I think the Redskins are a much bigger threat than people make them out to be. Because Seattle will be one dimensional, the Redskins will be able to capitalize on that. I'm picking a close game with Washington winning by a field goal.
New York Giants (10-6) @ Tampa Bay (9-7) New York played a really good game against NE on Saturday and I honestly expect them to carry that in to this game. They are notorious for sucking in the playoffs in the past few seasons but I think they'll be able to take on Bucs. The Bucs defense is going to give them a run for their money though, but then again, the Giants defense is going to give TB a really tough time as well. I think this is going to be a pretty close game as well.