HIV vaccine trial approved by FDA

[Restrat]

Tests, or rather studies, would first have to be done on the effects of certain actions on the risk of HIV. Now, I don't know if this was done or not yet, but it would have to be done to determine the standard deviation and to verify if the results are significant enough. If 50% of the control group get it and 40% get it in the experimental group, these numbers mean nothing without the right context and correct statistical figures.

This has been done since AIDS was first identified. Also, if the sample size was large enough, it wouldn't matter- all those risk differences would be distributed equally.

[Salodin]

Anal sex puts anyone at higher risk due to the lining of the anus being so weak/thin/sensitive.

Compared to just regular sex being easy to transfer hiv...?

[Restrat]

yes, the act itself is more risky than vaginal sex

[hey]

It amazes me how easily people will dismiss Science, while having no fucking clue what is even happening.

[Deejay]

Tests, or rather studies, would first have to be done on the effects of certain actions on the risk of HIV. Now, I don't know if this was done or not yet

really bro?

[Kuya]

Sooooo nobody wants to say high risk peeps are the gays, huh?

Meteora couldn't wait to post this btw.

[Chun Liroy]

really bro?

No, I didn't look up whether or not that the use of needles was quantified into a percentage increase in your risk for HIV, or what that percentage is. So, what is that well known statistic Deejay?

[Milkster]

They don't have that brand spanking new thing called Sexual Education in most schools yet...

[Kuya]

No, I didn't look up whether or not that the use of needles was quantified into a percentage increase in your risk for HIV, or what that percentage is. So, what is that well known statistic Deejay?

What are you asking for exactly? How do they prove what actions lead to higher incidences of hiv infection?

[Chun Liroy]

No. It's clear that there are certain lifestyles, choices and actions that lead to increased risk for HIV infection. I'm asking for them to be quantified, and since apparently it is well known that they were quantified at one point, what is that % increase that an action adds to the probability that a person is to contract HIV.

[Deejay]

No, I didn't look up whether or not that the use of needles was quantified into a percentage increase in your risk for HIV, or what that percentage is. So, what is that well known statistic Deejay?

I would but I really don't feel like bothering myself right now.

[Talint]

I'm curious to know what a "killed whole virus" vaccine is, and it's effectiveness.

[Kuya]

No. It's clear that there are certain lifestyles, choices and actions that lead to increased risk for HIV infection. I'm asking for them to be quantified, and since apparently it is well known that they were quantified at one point, what is that % increase that an action adds to the probability that a person is to contract HIV.

Check the CDC's site or some gay oriented health organization.

[Deejay]

I'm curious to know what a "killed whole virus" vaccine is, and it's effectiveness.

here come the conpiracy theorists

we're all gonna become zombies y'all

[Mazmaz]

It amazes me how easily people will dismiss Science, while having no fucking clue what is even happening.

I'm not dismissing science (why did you capitalize the S lol) but it's one thing to have psych experiments with a control group and an experimental group and go "lul how different was experiment's response compared to the control's, oh and everything is controlled for", and a totally different thing to go "let's give 3000 people HIV vaccines and hope the control group gets HIV".

Pardon me for being a little more skeptical about statistical analysis when it comes to stuff more complex than shitty social psych experiments.

[Talint]

here come the conpiracy theorists

we're all gonna become zombies y'all

...the hell? You're misunderstanding what I'm saying.

As a gay male, I have a vested interest in a HIV vaccine. As such, I want to know what a "killed whole virus" is, as I've never heard of it before; and how effective such vaccines are.

Luckily, wikipedia has an answer:

Some vaccines contain killed, but previously virulent, micro-organisms that have been destroyed with chemicals, heat, radioactivity or antibiotics. Examples are the influenza vaccine, cholera vaccine, bubonic plague vaccine, polio vaccine, hepatitis A vaccine, and rabies vaccine.

[Deejay]

Yeah, there are a lot of popular vaccines that use weakened or killed strands of a virus. I thought that much was known already.

[Chun Liroy]

Yeah, there are a lot of popular vaccines that use weakened or killed strands of a virus. I thought that much was known already.

Gays are dumb. Duh. Let's inject them with HIV to properly test this vaccine.

[Maguspk]

'Risk' is ambiguous.

The terms you want to use are 'exposure' and 'resistance'. There are people who are genetically resistant to HIV thanks to an absence of the CCR5 gene which prevents the production of a protein which is used by most strains of HIV bind to and subsequently enter the cell.

[kuronosan]

I'm curious to know what a "killed whole virus" vaccine is, and it's effectiveness.

Basically the DNA has been rendered useless but the epitopes remain, which is all your immune system needs to make antibodies. Essentially either the capsid surface proteins are intact or the viral DNA has been denatured to the point where it is no longer infectious. It's almost impossible to consider the entire virus "killed" because there's no way to really measure it (especially given the high mutation rate) unless you give it to someone who doesn't already have it.

tl;dr: No way to test the effectiveness of a vaccine without infecting someone who is willing to contract HIV.