"We're doing really well, and Mike is going to be in charge," Trump said, noting Pence's experience as governor of Indiana made him adept at working with state and local health authorities.
"This is not a czar," he said.
Trump said he would add a specialist from the State Department to the White House team, though he did not immediately name that person.
"We're ready to adapt and ready to do whatever we have to as the disease spreads, if it spreads," he said.
"As a former governor of the state with the first MERS case, I know full well the importance of presidential leadership and administration leadership and the vital role" of state and local agencies, Pence said, referring to the Middle East Respiratory Syndrome.
"USA in great shape!" he wrote in a Wednesday tweet. "By the way, we have not had one death. Let's keep it that way!"
Trump also lashed out at news outlets, saying, "Low Ratings Fake News MSDNC (Comcast) & @CNN are doing everything possible to make the Caronavirus look as bad as possible, including panicking markets, if possible."