Month Eight: Crashing Out Over A Podcaster

[arus2001]

Watched this the other day, Bernie one of like 5% of dem reps who actually understands connecting to and talking to working people. Other 95% don't give a shit and it's not gonna change as they constantly point to other groups for having lost 2024 instead of their shit politics and shit way of doing things.

More or less why while the vid feels good, it means nothing when your potential converts don't have a party to hop to in the concentrated numbers that mean anything. Cue the old Schumer quote about abandoning 1 west virginian to pick up 3 philadelphians or some shit.

[Xno Kappa]

I can't imagine a scenario where Big Pharma doesn't respond to this nonsense.

[Obsidian]

If they ever want FDA approval for anything ever again they're gonna shut up and eat it.

[Tyche]

I made a long post somewhere on this forum like 2 months ago talking about leucovorin. None of you are referencing it's use case correctly.

[Tyche]

RFK may not either. IDK, I haven't read anything about this yet.

Edit: I posted about a month ago, I pulled the research around 2m ago I think.

[Tyche]

The Wall Street journal is reporting what RFK Jr is putting in his autism report. He is reporting that Tylenol could be a cause and folic acid deficiency could be a cause. Neither is a novel idea. It's been reported and studied before.

So now I'm going to get a little deep in the weeds about some research that I'd done. This should be a spotlight on why the public should not do their own research. My wife works for a chemo infusion center, so she works with oncologists. One of the other nurses that she works with also has a kid with autism, and she was talking about a study she had seen about leukovorin, also known as folinic acid and commonly used alongside some chemo meds to help with symptoms, could be helpful for specifically speech delays in autism. My wife asked the oncologist about it, but he had never heard of it for autism. I went online trying to look up the studies and I found most of the studies had the same author and researcher. So then I researched the specific author of most of these studies and found out where he worked and what type of center it was and if it was some type of hokey bullshit. Even after that, I texted a doctor friend who I knew was working at the hospital that night and had him get on our database subscriptions and look into it there. I literally spent days to see if this specific treatment was bullshit, days. After talking to quite a few people and talking to our pediatrician, our pediatrician, who also had never heard of it, said that he would give us a referral if we could find someone that does it. But I know that aspect of it seems legitimate.

Anyway, me, with a master's degree in a healthcare field and almost 15 years of experience in the field, did all of that research for one specific treatment for one specific symptom. Imagine the type of rigorous research the people like rfk are doing.

^

[Tyche]

I'm also pretty certain that it was only studied and correlated when transfused intravenously. So Dr Ozs supplement company wouldn't benefit. This is a very specific medication that's infused in an infusion center. Typically an oncology center. It doesn't reverse autism. It helps with speech disorders. That's all. Speech. It's not some miracle drug. Doesn't work 100%. The evidence is compelling, not conclusive. If money gets thrown at it for further research, maybe some good can come from it.

Also, everything I've been told by people who order this multiple times a day is that it is, generally speaking, harmless. No one expressed any dismay at the thought of a child receiving it.

I'm excited to see career researchers dig through the data to tell me how I fucked up the research.

[Cail]

ABC announced Jimmy Kimmel returning to air on Tuesday

[Obsidian]

I think the actual problem is that they're about to upend decades of advice to scare pregnant women out of taking the only approved pain relief they have access to, and doing so based on a flawed study.

Whether or not Dr Oz or someone else close to Trump is going to make shitloads of money off them doing so is a separate issue, and whether or not folinic acid is even helpful is a tertiary issue.

[TummieGaruda]

ABC announced Jimmy Kimmel returning to air on Tuesday

He better not have been forced to make an on air apology…

[Madeline]

Ain't no way he'd come back if they made him do that. He already essentially told toilet paper and Kirk's family both to fuck off when they asked for apologies.

He'd be seen as forever spineless and people would want him right back off the air.

I'd say it's important to remember there were rumblings of the execs saying they pulled him for his safety and stuff. It's not exactly safe out there right now I'd imagine when the right is so charged up over this racist, misogynist, regressionist asshat's death.

I'm not saying it was a good move or agreeing with it, but that the whole situation's just kinda shit.

[archibaldcrane]

While leucovorin for chemo patients is typically an IV infusion, there's also oral administered leucovorin pills, which were used in the promising autism trials.

Notable that this treatment for autism-related speech is only seen as effective in the percentage of autism patients who are "folate receptor alpha autoantibody positive" which is only ~50-60% of autism-diagnosed children.

Small trial study results here: https://pmc.ncbi.nlm.nih.gov/articles/PMC7477301/#S17

[archibaldcrane]

Also the amounts of folinic acid used in the trial (2mg/kg/day) are WAY higher than the off-the-shelf folinic acid supplements you can find. 20mg twice a day for a typical-weight 5 year old isn't going to be accomplished by 800mcg/pill OTC folinic acid supplements.

[Salodin]

ABC announced Jimmy Kimmel returning to air on Tuesday

It's the right move but now they just look extra weak because they were scared enough to do it to begin with. Shouldn't have been scared little bitches to begin with

Sent from my SM-S936U using Tapatalk

[Kaslo]

https://x.com/TheOnion/status/1970198424336155113

[6souls]

ABC announced Jimmy Kimmel returning to air on Tuesday

Speaking of. That Kirk special that was supposed to air on Sinclair stations last Friday was replaced with a Family Fued rerun and the special was uploaded to YouTube.

[Mertron]

yep they’re doing the Tylenol presser now, trump just said people should “try to tough it out”

fucking lol

[kuronosan]

YOU CUT FUCKING FUNDING FOR FUCKING MEDICAID AND CHIPS YOU PIECES OF SHIT GOD I'VE STARTED TO FUCKING HATE YOU

[kuronosan]

I fucking hate ALL of these fucking grifting shit bags.

[zoobernut]

This really sucks because all the antivax people have been rallying against science and Dr.s and recommendations for years and now they have their people in positions of power and now all of the Dr.s and people who follow the science have to reverse the message and say "Don't listen to the FDA and CDC and "experts" they are quacks. Follow the science." It is going to make it even harder to recover from all of this.

Does this mean that antivaxxers are wrong though? Are they going to believe in vaccines again if they don't cause autism?