So this is my idea about how it'll go down. House euthanizing 13 isn't too far fetched, esp. if they're bringing her back right as the season ends. Maybe this sends him into some deep depression and is reminded of Kutner's suicide. Everything seems to be going wrong again in his life with Wilson's diagnosis, Dominika leaving, Cuddy not working out and now murdering one of his former colleagues. I hate to think House would choose suicide, but during that whole Cuddy arc when he jumped from the hotel into the pool, I really thought he was gonna try to end it there. Somebody earlier mentioned something about a possible OD and he meets god or something and it ends so we don't know if it was real or he was in some kind of dream state, that shit would be epic too.