Robot achieves scientific first
By Clive Cookson, Science Editor
Published: April 2 2009 19:17 | Last updated: April 2 2009 19:17
A laboratory robot called Adam has been hailed as the first machine in history to have discovered new scientific knowledge independently of its human creators.
Adam formed a hypothesis on the genetics of bakers’ yeast and carried out experiments to test its predictions, without intervention from its makers at Aberystwyth University.
The result was a series of “simple but useful” discoveries, confirmed by human scientists, about the gene coding for yeast enzymes. The research is published in the journal Science.
Professor Ross King, the chief creator of Adam, said robots would not supplant human researchers but make their work more productive and interesting.
“Ultimately we hope to have teams of human and robot scientists working together in laboratories,” he said.
Adam is the result of a five-year collaboration between computer scientists and biologists at Aberystwyth and Cambridge universities.
The researchers endowed Adam with a huge database of yeast biology, automated hardware to carry out experiments, supplies of yeast cells and lab chemicals, and powerful artificial intelligence software.
Although they did not intervene directly in Adam’s experiments, they did stand by to fix technical glitches, add chemicals and remove waste.
The team has just completed a successor robot called Eve, which is about to work with Adam on a series of experiments designed to find new drugs to treat tropical diseases such as malaria and schistosomiasis.
“Adam is a prototype,” says Prof King. “Eve is better designed and more elegant.”
In the new experiments, Adam and Eve will work together to devise and carry out tests on thousands of chemical compounds to discover antimalarial drugs.
FT.com / UK - Robot achieves scientific first
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Original Article
Abstract
The basis of science is the hypothetico-deductive method and the recording of experiments in sufficient detail to enable reproducibility. We report the development of Robot Scientist "Adam," which advances the automation of both. Adam has autonomously generated functional genomics hypotheses about the yeast Saccharomyces cerevisiae and experimentally tested these hypotheses by using laboratory automation. We have confirmed Adam's conclusions through manual experiments. To describe Adam's research, we have developed an ontology and logical language. The resulting formalization involves over 10,000 different research units in a nested treelike structure, 10 levels deep, that relates the 6.6 million biomass measurements to their logical description. This formalization describes how a machine contributed to scientific knowledge.
Perty picture of 'Adam'
http://i76.photobucket.com/albums/j1.../324_85_F1.jpg
The Automation of Science
Ross D. King, et al (3 April 2009)
Science 324 (5923), 85. [DOI: 10.1126/science.1165620]
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It's not a small machine at all, but the fact that it thought about what it was going to do before it did it and didn't require human input into what to do is a big step.
also inb4 Skynet
XI Wiki



