Ok, I've never had my framerate drop below 23 FPS, even at Whitegate AH and in Dynamis unless I max out DrawDistance. At a set of DrawDistance 5, lowest FPS is 21. At a set DrawDistance 20, lowest FPS is 18. I personally don't like how things look with DD maxed out anyway, though, so you'll never see me going that high (ie. Bastok backdrop, trees in Zi'tah, etc).
I've posted stats before, but I'll go ahead and reiterate:
ASUS Maximus II Formula LGA 775 Intel P45 ATX Intel Motherboard
Intel Core 2 Quad Q9550 Yorkfield 2.83GHz
Kingston 2GB 240-Pin DDR2 SDRAM DDR2 800 (PC2 6400)
2x (utilizing crossfire) ASUS EAH4870 DK/HTDI/1GD5 Radeon HD 4870 1GB 256-bit GDDR5 PCI Express 2.0 x16
Creative Sound Blaster X-Fi XtremeGamer Fatal1ty Pro
These components are nice, but as you see they are not cutting edge. Much newer stuff out nowadays. All of these components were purchased back in mid-late 2008.
Current video driver is vanilla 9.5. I'm aware 9.6 is out but haven't had a reason to update to it yet.
http://www.aethernavale.net/Media/images/videosetup.jpg
Yes, I overclock my CPU (3.6~4.0Ghz) and my video cards. Yes, I tweak the hell out of my registry. Your mileage may vary.