
Originally Posted by
Kaeko
I believe the only thing ever on the market that helped to clear acne permanently was accutane (Retinoids) as panda mentioned. It literally shrinks the size and production of your sebum glands. It had a ton of really serious side-effects though. If you do decide to get this (can you still get this?), just be aware of the side-effects. Bad acne can really hurt self-esteem, so for many it may be worth it - just realize that some of the side effects can be permanent - even after you stop taking it.
Outside of Accutane, meds you get are typically antibiotic related (since acne is caused by bacteria) - for instance your Minocycline. The problem with ongoing acne is you're killing off most of the bacteria when you start on the medication - face clears up a bit - but you end up leaving the resistant bacteria and selecting for its growth. So oftentimes you take the med, clear up, then it flares back up to normal or even worse months later (resistant bacteria selected). At this point, the antibiotic is useless because the thing it's trying to get rid of is resistant - and yet you still have to deal with all its side effects.
1 practical tip that may help you is if you sleep with your face to the side, try changing your pillow sheets very often. Those sheets can build up a lot of oil and your face is pressing right against it for hours at a time at night if you sleep sideways.