I'm not a runner so I can't offer any insightful experience. But the idea of running barefoot has been gaining a lot of interest lately. You can read about it
here,
here, or
here. In particular the
Vibram Five Fingers seem to be popular, if you're not afraid of looking goofy (but if it's actually healthier than maybe screw appearance).
Supposedly when a person is barefoot they change the way they run that is gentler on the body. Much of the support for barefoot running seems to be based on a book by
Christopher McDougall titled "Born to Run". In it he studies native tribes who have been running for centuries without modern shoes and finds that they have none of the common health problems you'd expect.
Like I said I'm not an experienced runner so I really can't speak to the truth or falsity of their claims. It seems plausible at least, but the whole wisdom-of-the-natives aspect makes me wonder if it's just coming from Luddites who hate all things modern. I do know that both my mother and step-father were runners, and over the years their knees have basically been destroyed to the point they can't run like they used to. Requiring multiple surgeries on their knees. And so I think it's at least worth some consideration to look into what's most healthy for you. I'd be interested to know if anyone on BG has tried them or has read this guys book etc.