New theories on cell death

[Kuya]

http://www.msnbc.msn.com/id/18368186/si ... /?GT1=9951

May 7, 2007 issue - Consider someone who has just died of a heart attack. His organs are intact, he hasn't lost blood. All that's happened is his heart has stopped beating—the definition of "clinical death"—and his brain has shut down to conserve oxygen. But what has actually died?

But if the cells are still alive, why can't doctors revive someone who has been dead for an hour? Because once the cells have been without oxygen for more than five minutes, they die when their oxygen supply is resumed. It was that "astounding" discovery, Becker says, that led him to his post as the director of Penn's Center for Resuscitation Science, a newly created research institute operating on one of medicine's newest frontiers: treating the dead.

"It looks to us," says Becker, "as if the cellular surveillance mechanism cannot tell the difference between a cancer cell and a cell being reperfused with oxygen. Something throws the switch that makes the cell die."

With this realization came another: that standard emergency-room procedure has it exactly backward. When someone collapses on the street of cardiac arrest, if he's lucky he will receive immediate CPR, maintaining circulation until he can be revived in the hospital. But the rest will have gone 10 or 15 minutes or more without a heartbeat by the time they reach the emergency department. And then what happens? "We give them oxygen," Becker says. "We jolt the heart with the paddles, we pump in epinephrine to force it to beat, so it's taking up more oxygen." Blood-starved heart muscle is suddenly flooded with oxygen, precisely the situation that leads to cell death. Instead, Becker says, we should aim to reduce oxygen uptake, slow metabolism and adjust the blood chemistry for gradual and safe reperfusion.


Its amazing how we had it completely backwards, just goes to show you can't ever trust current science 100% of the time.

[Senoska]

Has this been proven or is this some dude with a "Theory"?

[Ichthyos]

Yeah I showed this article to my friend in med school yesterday actually, and she said that they take this kind of thing into account for organ transplants and stuff. There are apparently drugs that they can administer to lessen the effects of reperfusion. There's definitely more room for research in the area though.

[Kuya]

Has this been proven or is this some dude with a "Theory"?

Read the link, they have tested it, and came out with a 80% survival rate.

[Mysterio]

Has this been proven or is this some dude with a "Theory"?

Read the link, they have tasted it, and came out with a 80% survival rate.

mmm sounds yummy.

[thestalkmore]

Has this been proven or is this some dude with a "Theory"?

Read the link, they have tasted it, and came out with a 80% survival rate.

mmm sounds yummy.

Exactly what I was thinking, delicious!

[Kuya]

Has this been proven or is this some dude with a "Theory"?

Read the link, they have tested it, and came out with a 80% survival rate.

mmm sounds yummy.

Exactly what I was thinking, delicious!

damn you typos

fixed it for ya bastids

[Keno]

You guys realize this is one step prior to zombies, right?

[-Omni]

You guys realize this is one step prior to zombies, right?

YES, AND I AM TOTALLY EXCITED.

[Ace-o-fire]

You guys realize this is one step prior to zombies, right?

YES, AND I AM TOTALLY EXCITED.

i will be never more thankful then to my friend for giving me that zombie survival book if it becomes true.

[Devek]

Next time I see someone having a heart attack I will hand them a cigarette

[Kaliden]

You guys realize this is one step prior to zombies, right?

YES, AND I AM TOTALLY EXCITED.

I've already gathered my ammunition and survival equipment.

[Intense]

You guys realize this is one step prior to zombies, right?

YES, AND I AM TOTALLY EXCITED.

I've already gathered my ammunition and survival equipment.

RL Resident Evil if you please.

[Kiro]

Gather together in some big ass mall when the planet becomes infested with zombies. /bg/ zombie kill squad unite!

[Intense]

Gather together in some big ass mall when the planet becomes infested with zombies. /bg/ zombie kill squad unite!

Oooooh wasnt that a setting from one of the Silent Hills? :D

[Kiro]

Gather together in some big ass mall when the planet becomes infested with zombies. /bg/ zombie kill squad unite!

Oooooh wasnt that a setting from one of the Silent Hills? :D

I have no clue, I haven't watched a zombie movie in a long ass time. :<

[arlania]

Gather together in some big ass mall when the planet becomes infested with zombies. /bg/ zombie kill squad unite!

Fuck malls, go to Wal-mart. It has everything you need.


Mall setting was from Dawn of the Dead.

[Intense]

Gather together in some big ass mall when the planet becomes infested with zombies. /bg/ zombie kill squad unite!

Oooooh wasnt that a setting from one of the Silent Hills? :D

I have no clue, I haven't watched a zombie movie in a long ass time. :<

No no, the games. And yeah I looked it up and it was silent Hill 3. I only played it bc I thought the main char was a hottie. :3

http://www.ambogiochi.it/images/SilentHill3_b.jpg

[Khamsin]

So does this research indicate whether or not people resuscitated in this fashion experience and increased craving for human brains?

[arlania]

So does this research indicate whether or not people resuscitated in this fashion experience and increased craving for human brains?

No, but they do harbor an ill will towards a certain pharmaceutical company...